How KYMRIAH May Help

How KYMRIAH differs from traditional therapies

Traditional therapies (such as pills, chemotherapy, and stem cell transplant) for r/r FL may involve indefinite repeated cycles of treatment. KYMRIAH^® (tisagenlecleucel) uses your own immune system to potentially fight your cancer with a single infusion—with the goal of breaking the continuous treatment cycle of r/r FL.

Is KYMRIAH effective?

KYMRIAH was studied in 90 adult patients with FL who had failed 2 or more other types of therapy. KYMRIAH delivered strong efficacy with durable responses. Nearly 90% of patients responded to treatment with KYMRIAH. Of these patients, 68% had complete response (all signs of cancer disappeared) and 18% a partial response (decrease in cancer cells within the body).

86% of patients (77 of 90) responded to treatment with KYMRIAH, which means the cancer disappeared or was significantly reduced after treatment.
68% of patients (61 of 90) achieved a complete response, which means all signs of cancer disappeared.
18% of patients (16 of 90) achieved a partial response, which means there was a decrease in the number of cancer cells within the body.

Most of the patients who achieved a response were still in response 12 months after treatment (about 55 of 77 patients).

Do I need follow-up treatment after KYMRIAH?

Because KYMRIAH is a single infusion, patients may avoid the repeated treatment cycles of conventional chemotherapy. In a clinical study, ~8 of 10 patients did not require another anti-lymphoma treatment within 12 months after infusion of KYMRIAH.

Will KYMRIAH work for me?

The goal of KYMRIAH is to put your cancer into long-term remission (meaning the signs and symptoms of the cancer are reduced). KYMRIAH offers a chance at lasting remission. Hear from Trish, a real KYMRIAH patient about her treatment journey. Keep in mind that every patient is unique, and responses to treatment may vary depending on the individual.